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Your DNA Secrets to Weight Optimization

Our Genetic analysis will provide an in-depth perspective of how your specific genes impact your ability to lose weight and maintain a healthy profile. As an example, we will peel back your layers of the following genetic codes:

  • If your body is resistant to losing weight
  • How well your body is able to process carbohydrates in your diet
  • How much body fat you can lose through cardio exercise
  • How well your body is able to effectively absorb folate (a B-complex vitamin)
  • How sensitive your body is to the amount of fat in your diet
  • How your body responds to strength training
  • How sensitive your body is to the amount of protein in your diet

Your genes determine if your body is resistant to losing weight.

Specific Genes Analyzed: FTO, TCF7L2, MTNR1B, PPARG, BDNF, ABCB11

Based upon the genetic results of these specific predictors, studies have proven that individuals who carry the more “less desirable” forms of the genetic expressions have had a more challenging time losing weight and maintaining a healthy status quo. By understanding your genetic profile, your Genetix team will have the tools required to target your specific epigenetic profile. Together with our line of nutraceuticals, your specific program will provide every advantage to overcome any genetic shortfalls that are preventing you from achieving your weight loss goals.

Your genes determine how well your body is able to process carbohydrates in your diet.

Specific Gene Analyzed: IRS1

Interestingly, the IRS1 gene has a variant which impacts an individual’s insulin sensitivity and the metabolism of carbohydrates in the diet. The common notion is that because eating carbohydrates triggers a release of insulin, the more carbs consumed results in more body fat and weight gain. However, we now know that the type of carbohydrates consumed is as important as how many. Plus, the IRS1 gene influences insulin resistance and how we respond to a carbohydrate rich diet. In fact, one long-term study has shown that individuals who consumed a high carbohydrate, low fat, high fiber, plant food-rich diet, instead of processed carbohydrates with lower fiber content had a greater insulin sensitivity with lower insulin levels and associated resistance. This translated to more weight loss, compared to a lower carb, high fat diet. Thus, if we know someone has a genetic variant of the IRS1 gene, we can mitigate that deficiency with a tailored program consisting of our exclusive nutrigenomic line, along with a better understanding of how your body actually metabolizes the foods you eat.

Your genes determine how much body fat you can lose through cardio exercise.

Specific Genes Analyzed: ADRB2, LPL

The two specific genes analyzed in this test have a direct correlation with an individual’s ability to lose fat from a regular program of cardiovascular exercise. Studies have shown that a person with the “less desirable” variant of one or both of these genes has a greater challenge losing the same fat percentage from cardiovascular exercise as an individual with the “more desirable” form of the gene(s). If you have the “less desirable” variant, this is certainly not an endorsement to cease cardiovascular work. On the contrary, it simply means that you and your Genetix team have a better understanding of why cardio work alone will not produce the same results for two people. By unlocking the secrets to your genetic code, Genetix can work with you to create the perfect plan to help you achieve a sustainable platform for weight loss with a better quality of life.

Your genes determine how well your body is able to effectively absorb folate.

Specific Gene Analyzed: MTHFR

We see the MTHFR gene variant quite frequently. This gene is responsible for enzyme production which directly impacts a person’s ability to convert folic acid into a form which can be metabolized by the body, L-Methylfolate. If you have a variant of the MTHFR gene, high levels of folic acid are useless as your body will not make the enzyme necessary to convert it into the state which can be utilized for homocysteine conversion, muscle growth, metabolism, and glutathione production. Why is this important? For one, low levels of folate have been linked to anemia. More concerning though, is that one of the markers we assess in cardiovascular health revolves around homocysteine levels. High levels of this naturally occurring amino acid have been linked to cardiovascular disease and other chronic health conditions. If we know that you have an MTHFR gene mutation, we can easily overcome this barrier with our exclusive line of nutraceuticals to help lower homocysteine levels and allow your body to effectively process the folate it needs.

Your genes determine how sensitive your body is to the amount of fat in your diet.

Specific Genes Analyzed: PPARG, TCF7L2, APOA5, CRY2, MTNR1B, PPM1K

This genetic profile test helps us understand how you metabolize fats in your diet. Many people are under the false assumption that fats are bad. Quite the opposite, “good” fats are inherently necessary in a healthy daily diet. Individuals with variants in these genes have been shown in studies to have a greater challenge losing weight, shrinking waist circumference and lowering their Body Mass Index (BMI), than individuals who did not have the variant. When we then look at body fat location on the body, the mid-section is of significant concern since that particular area houses more cytokines (toxins) than other parts of the body. This has a greater detrimental impact on surrounding organs. Thus, your Genetix medical team is most concerned with helping you lose waist circumference and lowering your BMI. We have tools to aid fat metabolism to help you with the genetic battle.

Your genes determine how your body responds to strength training.

Specific Genes Analyzed: NRXN3, GNPDA2, LRRN6C, PRKD1, GPRC5B, SLC39A8, FTO, FLJ35779, MAP2K5, QPCTL-GIPR, NEGR1, LRP1B, MTCH2, MTIF3, RPL27A, SEC16B, FAIM2, FANCL, ETV5, TFAP2B

As we all work toward weight loss, one critical component to always factor within a comprehensive program includes resistance training to aid in the building of muscle. Cardiovascular exercise alone will assist in fat reduction, but it will also have a direct impact in muscle loss. To further assist in body fat reduction and muscle strengthening, resistance training must be incorporated. Individuals with a variant of these genes face greater challenges in reducing body fat percentages with resistance training. If your Genetix medical team has this knowledge, we can work with you to strategically craft a sustainable program that is individualized specific for your genetic makeup.

Your genes determine how sensitive your body is to the amount of protein in your diet.

Specific Gene Analyzed: FTO

Individuals with variants in the FTO gene variant often have greater challenges finding the composition balance in a protein, carbohydrate and fat daily diet. While this is a fairly common variant, these people tend to favor fattier foods, have challenges with portion control and have a higher incidence of being overweight with a higher BMI. Understanding how your body metabolizes food is as important as crafting a plan that is sustainable and enjoyable. If we see you have a variant in the FTO gene, we will incorporate that understanding into your individualized plan for overcoming this obstacle. All you need is the knowledge. Genetix has the tools.

Weight Optimization and YOUR DNA with Dr. Tim Church M.D., Ph.D., M.P.H.

Chief Medical Advisor Genetix Health Institute

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